Genealogical studies in families with oral clefts and reference families

Oral health-related quality of life of children with oral clefts and their families

Oral health problems can influence people's Quality of Life (QoL) because of pain, discomfort, limitations, and other esthetics problems, affecting their social life, feeding, daily activities, and the individual's well-being. To compare oral health-related quality of life (OHRQoL) of children with and without oral clefts and their families. 121 children aged from 2 to 6 years, from both sexes,...

Evidence that BCL3 plays a role in the etiology of nonsyndromic oral clefts in Brazilian families.

The BCL3 gene has been considered a susceptibility locus for nonsyndromic cleft lip with or without cleft palate (NSCL/P), based on association and linkage studies in some populations. We evaluated an intragenic marker at the BCL3 gene and the microsatellite D19S178 (1.1 cM distant from the BCL3 gene) among 98 infants born with NSCL/P and their parents, using the transmission disequilibrium tes...

Analysis of sequence data to identify potential risk variants for oral clefts in multiplex families

BACKGROUND Nonsyndromic oral clefts are craniofacial malformations, which include cleft lip with or without cleft palate. The etiology for oral clefts is complex with both genetic and environmental factors contributing to risk. Previous genome-wide association (GWAS) studies have identified multiple loci with small effects; however, many causal variants remain elusive. METHODS In this study, ...

Violence in Iranian Families

Comparison school bonding and interpersonal problems in students with unsupervised and abused families with normal

This study aimed to compare the school bonding and interpersonal problems in students with unsupervised and abused families with normal families in Bandar Lengeh. The sample consisted of 152 normal students and 81 unsupervised or abused students. Normal students were selected by the multi-stage cluster sampling method. Data were collected through two questionnaires: school bonding (Rezaei Shari...